This animated feature is about how the Justice League battles the Fatal Five, (Tharok, Emerald Empress, Validus, Mano and the Persuader). These events are based on the novel created by Jim Shooter. The full cast includes: Elyes Gabel as Thomas Kallor / Starboy (voice), Diane Guerrero as Jessica Cruz / Green Lantern (voice), Kevin Conroy as Batman (voice), Susan Eisenberg as Wonder Woman (voice), George Newbern as Superman (voice), Daniela Bobadilla as Miss Martian (voice), Kevin Michael richardson as Mr. Terrific / Kilowog / Additional Voices (voice), Noel Fisher as Brainiac 5 (voice), Peter Jessop as Tharok (voice), Tom Kenny as Bloodsport / Salaak / Jessica's Ring / Additional Voices (voice), Matthew Yang king as The Persuader / Arkham Director (voice), Sumalee Montano as Emerald Empress (voice), Philip Anthony-rodriguez as Mano (voice), Tara Strong as Saturn Girl / Harley Quinn / Poison Ivy / Additional Voices (voice) and Bruce Timm as Two-Face / Validus (voice).

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